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This program induces the glutathione-degrading enzyme CHAC1, thereby accelerating GSH degradation to 5-oxoproline and disrupting redox homeostasis

Some people may experience side effects which could include upset stomach, nausea, dry mouth, increased or decreased blood pressure, and headache

It is important to search for safe and low-cost alternative therapies for CF and, in this context, natural compounds and, mainly, caffeic acid phenethyl ester (CAPE) appear as promising strategies to assist in the treatment of the disease

In this review, we discuss the physiological significance of iron homeostasis in the body, the potential contribution of ferroptosis to the etiology and development of human diseases, along with the evidence supporting targeting ferroptosis as a therapeutic approach

Comprehensive guide to clozapine for pharmacy and medical students, covering mechanism of action, pharmacokinetics, adverse effects, monitoring requirements, and exam-style MCQs with explanations.