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Description
Ghofrani, H.-A
The 2 primary functions of this pathway are (1) the generation of NADPH for use in other reductive biosynthetic (anabolic) pathways and (2) to convert glucose carbons into ribose 5-phosphate (R5P) for the synthesis of the nucleotides and nucleic acids
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Indeed, ECs or transgenic mice harboring PAH-causing mutations exhibit substantially more Gln-derived carbon throughout the Krebs cycle than wild-type controls
H&E staining Mouse dorsal skin tissues were cut and soaked in 4% paraformaldehyde, placed at 4C for 48 h, dehydrated and embedded in paraffin, and sectioned to make tissue samples
Subcellular distribution of CoQ 9 is altered, which may explain the lowered oxygen consumption and ATP production phenotype of heterozygous Mclk1 +/ mitochondria [199,200]
