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5 UGT1A1 is a major enzyme involved in this process

10.1126/scitranslmed.3004404 35 BrownG

In contrast, marked up-regulation of several GST s was observed in most of the datasets

Journal of Neurochemistry, 48(3), 760764

In theory, due to the complex heterogeneous bacterial population consisting of growing and non-growing persister cells, 24,484,485 a drug combination approach targeting these two bacterial populations would be important to cure persistent infections, according to the Yin-Yang model