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Although bariatric surgery can lead to weight loss of at least 25% and long-term weight maintenance, it is not scalable at the population level, and many people are still afraid to have surgery because of the possibility of complications, [135, 136]

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The compound exists in a research context, not a therapeutic one

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The p K a of the 2 nitrogen has been shown in 13-C NMR studies of a model compound to be about 0.6 pH units higher than that of the 1 nitrogen, so in the absence of countervailing environmental effects, the form on the right will tend to predominate

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