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Description
A subgroup of T helper cells (also known as CD4 + cells) that is mainly involved in the cell-mediated immune response against intracellular pathogens such as bacteria by maximizing the efficacy of macrophages and cytotoxic T cells

Thiocarboxylation of molybdopterin synthase provides evidence for the mechanism of dithiolene formation in metal-binding pterins

Cell & Bioscience
Aug 11 2024 Van Tin et al., Cells, doi:10.3390/cells13161331 Spike Protein of SARS-CoV-2 Activates Cardiac Fibrogenesis through NLRP3 Inflammasomes and NF-B Signaling In vitro study showing that the SARS-CoV-2 spike protein can activate cardiac fibroblasts through ACE2-dependent mechanisms, leading to cardiac fibrosis via the NLRP3 inflammasome and NF-B signaling pathways

Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association

These observations are in line with the fact that tumors of the lung are highly mutated in KEAP1, the inhibitor of this pathway