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Both one- and two-tailed analyses were conducted and yielded consistent results

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However, various factors can lead to glutathione depletion, including poor diet, stress, aging, and certain medications, such as NSAIDs

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It inhibits class-I histone deacetylases, remodels chromatin and gene expression, activates an anti-inflammatory receptor, and competes with acetyl-CoA in anabolic reactions 264,379,380,381,382