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When FH is genetically variated, fumarate hydratase becomes defective, leading to fumarate accumulation increase, affecting a variety of metabolic pathways associated with it
After an acute insult AST rises more slowly and to a lesser extent than ALT
Accessed 03/04/2024
ACs significantly linked to MDD status and/or depression severity were carried forward in subsequent analyses examining whether the association was mainly driven by specific symptom profiles, by regressing the metabolite levels on each of the three symptom profile scales
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