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Moreover, the cytokine signatures have potential as biomarkers to differentiate the two types of IBD as CD primarily expresses Th1- and Th17-associated cytokines (IL-17, -23 and -32), whereas UC is an atypical Th2-with low IL-4 and high IL-5, -13, -15 and -33 [70]

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Regarding neovascularization, a key process for supplying blood to the healing tissue, the number of blood vessels tended to increase from day 7 to day 21 in all groups

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FDA will post its own background review of each substance at least two business days before the meeting

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In ( a-f ) values are mean s.d

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