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A similar mechanism has been described for the prion protein PrP, wherein its mislocalization to the cytosol enables aberrant binding to cytosolic ubiquitin ligase, sequestering the enzyme and reducing its functional availabilitythereby contributing to neurodegeneration 82

BBB dysfunction is associated with long COVID-induced cognitive impairment Given the significantly increased serum concentrations of S100, our data indicated that active and acute SARS-CoV-2 infection is associated with potential BBB dysfunction in individuals with neurological impairment

3-Pain: Women with fibroids experience more pain than women without fibroids

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