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Targeted metabolomics reveals that GPX4 overexpression and knockdown influenced the lethality of 12 ferroptosis inducers, highlighting the role of Gpx4 in ferroptosis regulation (Lou et al., 2024)

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Estrogen-dependent E2a/Pbx1 myeloid cell lines exhibit conditional differentiation that can be arrested by other leukemic oncoproteins
Serious or systemic side effects are much less common compared to other hormone therapies