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A dopaminergic receptor D1, D2, and D3 agonist, pramipexole has a greater affinity for D3 receptors

( D ) Lifespan survival curves of WT animals and intestinal SFP-1 overexpressing ( intestine::sfp-1,gonEx17) animals treated with EV or fat-5 RNAi

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Date, R.C

In conclusion, these studies showed an effect of APOE on L-carnitine, its metabolites and acylcarnitines with age in the brain parenchyma and in the cerebrovasculature up to mid-life, which suggest differences in age-related bioenergetic shift between alleles