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Variants in these genes, in combination with inadequate B-vitamins, and other essential methyl group donors, are associated with a decreased methylation index and thus an increased risk for disease

doi: 10.1016/j.freeradbiomed.2005.02.026 5 LeeSKimSMLeeRT

Importantly, inhibition of hyperglycemia-induced superoxide overproduction using a transgenic approach (superoxide dismutase [SOD]) also prevents long-term experimental diabetic nephropathy and retinopathy [143]

Thioredoxin and Thioredoxin Target Proteins: From Molecular Mechanisms to Functional Significance

159 Furthermore, BMAL1 is involved in BMSCs development and ossification by regulating Runx2 and Osx

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