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Science 358 , 522528 (2017)

The GCLC floxed X CaMKII-Cre mouse was named here as GCLC-KO for the sake of convenience

Unresolved inflammation results in formation of vulnerable plaques characterized by enhanced macrophage apoptosis and defective efferocytosis of apoptotic cells resulting in necrotic cell death leading to increased smooth muscle cell death, decreased extracellular matrix production, and collagen degradation by macrophage proteases

Although artificial intervertebral disc prostheses are unlikely to achieve the same level of popularity as prostheses in total knee and total hip arthroplasty in the short term, with the advancement of 3D bioprinting technology in the future and the discovery of suitable cell sources and scaffold materials, tissue engineering for the repair and regeneration of degenerative intervertebral discs will become a highly promising option

6d) Overall, further investigation in an in vivo model of atherosclerosis will be crucial to understanding how G6PD-d disrupts the balance of these proatherogenic and atheroprotective T cell effects

A chemical agent is herein understood to be a defined chemical molecule, usually a smaller, non-polymeric molecule (e.g