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Development of PIP 2 -based chemical probes has been difficult, as modification of the inositol group and/or the acyl chains decreases PLC binding, hydrolysis, and catalytic efficiency (Bruzik and Tsai, 1994

Enhanced metabolic rate*

A boxplot for one of the most significantly altered sphingolipids in plasma, HexCer(d18:1/22:0) (Fig

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Antimelanogenesis Pathway Comparison Studies MT1 serves as the positive control reference compound in studies screening inhibitors of the melanogenesis pathway