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This analysis may be superseded by an updated publication on the same topic

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Preclinical Findings (Animal & Cellular) Adipose NNMT inhibition increases energy expenditure and reduces fat mass

Vitamin B12 is a water-soluble vitamin and is derived almost entirely from certain foods such as meat, fish, shellfish, dairy products, eggs and edible algae

its use is typically limited to research contexts or compounding pharmacies

Effect on the gut microbiome: Studies in mouse models show that 5-Amino-1MQ, when combined with diet, affects the gut microbiome, which may have long-term metabolic effects