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& Lovestone, S
A.Al-RabeeahA
doi: 10.1016/j.clindermatol.2010.03.018
The process by which Astragalus membranaceus-Dioscorea opposita regulates the cell cycle and pathways to inhibit tumor cell proliferation is as follows: In CRC cells, the expression of cyclin D1 and CDK4 is inhibited by AS-IV, causing cell cycle arrest at the G0/G1 phase
As a reactive oxygen species (ROS), hydrogen peroxide plays an important role in communicating immune responses
Its ~5day halflife allows convenient onceweekly subcutaneous dosing [1]
