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Inactivation with GABA A and B agonists (muscimol and baclofen) (i) reduced the expression of behavioral (orienting/scanning) and cardiovascular (blood pressure and heart rate) conditioned threat responses during Pavlovian discriminative conditioning when a previously neutral stimulus (i.e., an auditory cue) became associated with an aversive event (i.e., a loud noise and (ii) accelerated extinction of conditioned cardiovascular and behavioral responses, when the conditioned stimulus no longer predicted the aversive event (i.e., rubber snake) [38]

[DOI] [PubMed] [Google Scholar] 13.Seko Y, Sumida Y, Tanaka S, et al

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We set a fold change threshold of 1 and a p-value threshold of less than 0.05 (Ltsch et al., 2024) The matrices were normalised using the sum and Pareto scaling methods before analysis