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PMCID: PMC4630702

The rationale rests more on theoretical benefit and observed clinical patterns than controlled trial evidence

Furthermore, ILC2s accumulate in the choroid plexus of aged mouse brains, and intracerebroventricular transfer of activated ILC2s was found to rejuvenate the aged brain and enhance cognitive function in aged mice, highlighting the lifespan-regulating role of ILC2s in CNS health and aging [137]

Frontiers in Pharmacology, 2017, 8: 904

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