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Feb 27 2020;20(5)doi:10.3390/s20051288 Signorelli SS, Platania I, Tomasello SD, et al

In addition to PHGDH, serine hydroxymethyltransferase (SHMT) is also implicated in tumorigenesis

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Loss of extracellular matrix is in part due to death of fibrous cap smooth muscle cells, resulting from macrophage-derived Fas receptor ligand (195), inflammatory cytokines (196), and oxidation products (Figure 5) (197,198)
