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VSMCs were cultured in medium with 1, 5, or 10 mmol/L LC for 48 h

MGST2 activation is downstream of CHOP CHOP is induced by ER stress before other mediators of cell death

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Factors influencing APAP-related hepatotoxicity The most essential determining factor in both the development and severity of APAP hepatotoxicity is the drugs ingested dose, but some argue that the length of time from APAP ingestion to N -acetylcysteine (NAC) therapy (time to NAC) is equally if not more important

GPX4 immunoreactivity is largely absent in these cells, although it can be seen in surrounding glia and white matter

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