glutathione glutamate toxicity mechanism of PAs in metabolism: downward red Full article: Reconsideration of the

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136 In addition, acquired astrocytopathies are prominent in hepatic encephalopathy (in which astrocytes lose their homoeostatic capabilities 137 ) and in neuromyelitis optica, in which the astrocyte protein, AQP4 is the subject of autoimmune attack, leading to dysfunction and death of astrocytes resulting in pronounced inflammation and degeneration of neural tissue

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SUPPLEMENTARY FIGURE S2 Box-and-whisker plot of the urine GPX4-to-creatinine ratio (UGCR) in anemia and non-anemia groups, further stratified into early- and late-stage CKD groups

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