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Increasing Hb pseudoperoxidase activity with KDS12025 mitigates oxidative stress and alleviates neurodegeneration in AD, PD, and ALS patients and increases the degree of aging, with broad applicability for numerous oxidative-stress-driven diseases.

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Chemical biotransformation of MC primarily takes place in the liver, in which chemically reactive and stable metabolites are formed via two processes, namely, oxidation by microsomal cytochrome P-450 and conjugation by GST