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Researchers frequently measure acylcarnitine profiles and mitochondrial respiration parameters in controlled experimental settings

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AM resulted in remarkable mitochondrial shrinkage, enhanced Fe 2+ and ROS levels, and significantly decreased mRNA and protein expression of SLC7A11 and GPX4 in breast cancer cells, indicating that AM suppressed cell growth and invasion via ferroptosis ( Venenum bufonis

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55 Hormonal factors Hormonal factors like long-term exposure to estrogen 56 and reproductive history influenced by factors such as late menopause, 57 early menarche for every year younger at menarche, 58 nulliparity, 59 and abortion 60 exhibit a connection to an elevated vulnerability to breast cancer