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NETs induce Fundc1 phosphorylation of endothelial cells, inhibit mitochondrial autophagy and lead to mitochondrial ROS overproduction and lipid peroxidation, thus inducing endothelial cell ferroptosis and microvascular dysfunction

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Regular Exercise Exercise, especially moderate-intensity aerobic exercise, has been shown to naturally boost glutathione levels by stimulating antioxidant enzyme activity in the body

2021A 26;22(17):9224

However, the roles of P2X7R and NF-B in microglia-associated neurotoxicity require more comprehensive understanding in HAND in future studies

Contribution statement RM prepared the samples, conducted the analyses, prepared the tables and figures, evaluated and interpreted the data and co-wrote the manuscript
