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EFSA Journal (2012)

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Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, Cotman CW, Ames BN: Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

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Thus, if several doses are administered over a short time frame (e.g., less than 24 hours), the phenobarbital level can be estimated with reasonable accuracy