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Splenectomy may be considered for patients with massive splenomegaly causing discomfort, hypersplenism resulting in excessive red cell destruction, or rising transfusion needs

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Innate immune responses in hepatitis B virus (HBV) infection

The capability for absolute quantification, demonstrated for CFTR (McShane et al., 2014), provides particular value for establishing precise physiological or pathological concentrations of key proteins involved in oxidative stress responses