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Additionally, SCFAs modulate immune-inflammatory responses through activation of G protein-coupled receptors

10.1016/j.ejbas.2016.12.002 3 GeberemeskelG

These may occur if: The injection was too shallow or too deep The fluid volume was too high for the site The product was too concentrated or acidic Local immune cells formed a small granuloma (harmless but annoying) Applying a warm compress can help disperse the fluid and reduce the lump

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however, further controlled trials are still required to establish its routine use [46, 52]
