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2009) and a lowering of GSH consumption by inhibiting the continuous GSH export (Minich et al

A B12 deficiency can happen due to age, low absorption, low IF levels, or diet

Awareness of this entity is essential for early diagnosis, appropriate management, and prognostication

Indeed, changing the pH from 0 to 14 changes the ORP by around 800 mV, whereas changing the H 2 by a factor of ten (0.16 mg/L to 1.6 mg/L) only changes the ORP by 29.58 mV

However, what is unclear from these studies is whether elevated serum B12 is a cause of increased mortality and related morbidities (e.g., cardiovascular disease, cancer), a consequence of other conditions associated with increased mortality (e.g., hematological, liver or kidney disease), or simply coincidental to these conditions