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25) that impair the absorption of dietary fats and therefore fat-soluble vitamins like vitamin E (see Nutrient interactions) (24)

Janelidze S, Hertze J, Zetterberg H, Landqvist Wald M, Santillo A, Blennow K, et al

Mehdi Y, Dufrasne I

Raman D, Baugher PJ, Thu YM, Richmond A

Low-calorie and low-sugar beverages are the best

In an experimental model of abdominal aortic aneurysm, topiramate markedly downregulated pro-inflammatory M1 macrophage activity, reduced the expression of TNF-, IL-1, and matrix metalloproteinase-9, and promoted a phenotypic shift of macrophages from M1 to M2, thereby mitigating pro-inflammatory activity and enhancing tissue repair processes ( These studies collectively suggest that topiramate exerts significant neuroprotective effects across various pathological models through its potent anti-inflammatory properties
