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For example, vegans/vegetarians and people suffering from atrophic gastritis or pernicious anaemia use B12 injections

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[DOI] [PMC free article] [PubMed] [Google Scholar] Minagar A, Shapshak P, Fujimura R, Ownby R, Heyes M, Eisdorfer C (2002) The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

Regulating the SAM/SAH Ratio The SAM/SAH ratio is influenced by several factors, including: Diet : Nutrients such as folate, vitamin B12, and methionine directly affect the SAM cycle, influencing the balance between SAM and SAH

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