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Aduhelm was tested in two such trials -- ENGAGE and EMERGE -- but these were discontinued in March 2019 after an independent data monitoring committee found that the medication didn't seem to be making enough of an impact

Vitamin B-12 status differs among pregnant, lactating, and control women with equivalent nutrient intakes. The Journal of Nutrition 145.7 (2015): 1507-1514

Research suggests the use of vitamin B12 supplements in those with kidney disease and a B12 deficiency, but fully understanding the risks and benefits of regular supplemental B12 in those without a deficit still requires more research

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