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K., Hellemann, G., Green, M

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Transcripts with altered rhythm in cKOt mice (model 5) demonstrated a bimodal distribution only in cKOt mice, while the phase was not biased in controls, which was expected for genes regulated by both the circadian clock and systemic signals (27)

Simultaneously, controls received an equal volume of saline 5 mL/kg intraperitoneally one time daily, or drinking water only (12 mL/rat/day), till sacrifice at the day 14 or day 30