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Furthermore, Grx1 mutants were susceptible to superoxide anion-induced oxidative stress, but Grx2 mutants were selectively sensitive to H 2 O 2 , showing that Grx1 and Grx2 operate differently in a yeast cell

Nanoparticle-mediated lipid metabolic reprogramming of t cells in tumor microenvironments for immunometabolic therapy

Further research revealed that the knockdown of heme oxygenase 1 (Hmox1) by siRNA resulted in a diminution of antioxidant factors GPX4 and FSP1 [32], along with an increased release of intracellular bacteria in Bacillus Calmette-Gurin (BCG)-infected macrophages [743]

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