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p53-pS15 is involved in regulating cell cycle arrest and apoptosis resistance in keloids Phospho-specific protein microarray was used to investigate the cell signaling profile in fibroblasts from keloid versus those from adjacent skin

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Given its essential role in the detoxification of lipid hydroperoxides, and its overexpression in most of myeloid malignancies, GPX4 inhibition has emerged as a promising therapeutic strategy to specifically trigger ferroptosis and eradicate myeloid leukemia cells