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First, in STZ-induced diabetic rats, Singh et al (106) and Higashi et al (107) found that oral administration of 40 mg/kg/day resveratrol is beneficial in the pharmacotherapy of diabetes and its secondary complications, such as cataracts, through the attenuation of oxidative damage to lens proteins

One more realistic animal model is that induced by cecal ligation and puncture (CLP), where puncturing the cecum causes the release of fecal material in the peritoneum that results in a polymicrobial peritoneal sepsis

(3) termination

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In addition, high CVAI or NVAI was significantly associated with a high CKD prevalence in both men (odds ratio [OR], 2.14