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Routine clinical pharmacology studies such as SAD, MAD, mass-balance, and DDI studies were not performed in the case of NAC approvals, limiting the available information on the drug, which has been extensively used since the 1960s

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A recent study by the Chinese University of Hong Kong designed a panel of 31 multi-kingdom markers including bacteria, viruses, fungi, and other microorganisms and showed a promising AUC of 0.91 for ASD diagnosis