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Permeability changes have not been verified yet in the constipation-predominant IBS (IBS-C) subgroup by other investigations, whereas patients with mixed bowel habits (IBS-M) have not been investigated so far

Are these tablets safe for daily use
doi: 10.1073/pnas.0510565103 27 RavegniniGCargninSSammariniGZanottiFBermejoJLHreliaPet al

Jan-Feb 2007;13(1):103-109
And he goes, you know what, I have no pain in my joints