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This combination represents the most widely studied GH secretagogue pairing, based on the well-characterized synergistic interaction between GHRH and GHSR signaling at the pituitary level

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In addition, pathogen challenge elicited particularly dynamic responses of GSTF8: by 2 h after inoculation the corresponding transcript was already significantly up-regulated and the post-translational protein modifications detected were specific for incompatible interactions (Jones et al., 2004)
