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There are no definitive dosing guidelines from regulatory bodies for DSIP in sleep disorders or for promoting deep sleep in healthy populations

Hu MC, Shi M, Gillings N, Flores B, Takahashi M, Kuro-o M, Moe OW (2017) Recombinant -klotho may be prophylactic and therapeutic for acute to chronic kidney disease progression and uremic cardiomyopathy

(2015) 149:158798.e11

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For example, Kang et al

Rev Environ Health 2000;15:1342