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Description
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

McCann JC, Hudes M, Ames BN

JCI Insight 6 , e149271 (2021)

Ca 2+ enters cells in different ways including cation channels

The data fits to rate constants of: k 1 of 204 2 s 1 , k 2 of 0.22 0.01 s 1 , a k 3 of 0.005 0.001 s 1 , and a k 4 of 0.00016 0.0001 s 1

Residues around the active-channel have an important effect on enzyme activity [35]