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Lysosomes also serve as signaling hubs to monitor the intracellular levels of nutrients and energy by acting as platforms for the assembly of multiple signaling pathways, such as mammalian target of rapamycin complex 1 (mTORC1) and adenosine 5-monophosphate (AMP)-activated protein kinase (AMPK)

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Male wild-type (WT) mice and Gpx1 KO mice were intravenously injected with Con A (10mg/kg), and then killed after 8h after Con A injection

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