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The depletion of GSH increases the susceptibility of cells to ferroptosis, while GSH synthesis confers resistance to ferroptosis [20, 21]

Neuroinflammation causes the most common manifestations of this disease including headaches, fatigue, insomnia, depression, anxiety, among others

[Google Scholar] 68.Bagchi D., Bagchi M., Stohs S.J., Das D.K., Ray S.D., Kuszynski C.A., Joshi S.S., Pruess H.G

Ferroptosis induction triggers immunogenic cell death (ICD) and the release of damage-associated molecular patterns (DAMPs), which promotes dendritic cell maturation and enhances CD8 + T cell cytotoxicity

To see whether this is also specifically true for ferroptosis-related genes, we analyzed the 44 ferroptosis-related genes in the AMPA-AD dataset where AD-DEGs were compared between genders (Table 3)

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