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We evaluated the effect of low concentrations of RSL3 in combination with either a high or low dose of COJEC on cell viability using the chemoresistant organoid models LU-NB-1 and LU-NB-3R (Figure S4A-B and Table S1)

They measured the oxygen consumption rate (OCR), an indicator of mitochondrial electron transport chain (ETC) activity

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A black box is placed at the end of the beam as the completion point

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