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By targeting KRAS G12C with ARS-1620, the phosphorylation of multiple RTKs was augmented in different ways across diverse KRAS G12C mutant models (95)

Acid-cleavable linkers, such as hydrazone and carbonate linkers, break down in acidic environments and are often used to target the acidic lysosomal compartments within cells
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doi: 10.3390/foods12040791 Summary Keywords crocodilian oil, anti-inflammatory, skin health, energy metabolism, antimicrobial activity, scar reduction Citation Huang Y, Zheng X, Ming X, Jiao Q, Xiao W, Wu Q, Zheng L, Zeng Y, Cheng S, Wang R, Yang J, Bian Y and Yao J (2025) Recent advances in crocodilian oil research: bioactive components and potential therapeutic applications

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