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Accumulated iron can also induce the transition of a-syn from an alpha-helical to a beta-sheet structure, a conformational feature of Lewy bodies in the substantia nigra (SN) of PD patients, potentially contributing to the onset of PD (Figure 4D
PMID: 23950538
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Cancer On the one hand, tissue damage associated with cell death leads to chronic inflammation, which is a high risk for tumorigenesis
J Plant Stud 8(1):10
Beal MF, Brouillet E, Jenkins B, Henshaw R, Rosen B, Hyman BT
