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To better comprehend the role of an increased intestinal permeability in GI diseases, it is crucial to understand some basic concepts on how different molecules cross the intestinal epithelium and how intestinal permeability can be evaluated in humans

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Metformin reverses fatty liver disease in obese, leptin-deficient mice

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Oxidative stress through the production of free radicals does have some potentially beneficial effects for the host in terms of antibacterial action, immune defense, and signal transduction

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