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In the next step, a second equivalent of GSH reacts with the glutathionylated intermediate to form the stable product GSSG, and this allows the release of the reduced selenium or cystine for the next catalytic cycle (see Figure 4 for an example of GPX4 oxidoreductase mechanism)

As a result, a majority of fungal BGCs are now heterologously expressed in more closely related filamentous fungal hosts

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Glutathione and Its Antiaging and Antimelanogenic Effects. Clinical, Cosmetic and Investigational Dermatology , vol

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