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One mechanisms of action involves the stimulation of networks of neurons resulting in decreased pain sensation (Vance 2014)

Women between 65 and 70 years of age were supplemented for 24 weeks with either 1500 mg l-carnitine-l-tartrate or an isonitrogenous placebo per day in a double-blind fashion

A small piece of adhesive tape was attached to each palm of the forepaw, and the mouse was placed in the test cage

Add 10g (approximately 3 teaspoons) to 250mL water before training

Interestingly, the level of Akkermansia was lower in P479L+V compared to Wt+V mice, which could indicate differential effects following rotenone exposure