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doi: 10.1515/bmc-2022-0046 [DOI] [PubMed] [Google Scholar] 28.Coryell PR, Diekman BO, Loeser RF

Covalent/irreversible inhibitors target the redox/catalytic apparatus of TGR with almost no recognition elements that give affinity and selectivity for TGR over off-targets and the cellular redox apparatus resulting in undesirable cross-reactions and low specificity in vivo 25

Biochem Biophys Res Commun 519:533539 Sun Y, Kang J, Guan X, Xu H, Wang X, Deng Y (2021) Regulation of endoplasmic reticulum stress on the damage and apoptosis of renal tubular epithelial cells induced by calcium oxalate crystals

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Supports Mental Health and Mood Regulation Adequate B12 levels are associated with maintaining healthy levels of neurotransmitters such as serotonin and dopamine