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On the other hand, PGC-1/NRF1 regulates FUNDC1-mediated mitophagy through transcription, promoting mitochondrial biogenesis during the process of mitochondrial autophagy, accelerating mitochondrial turnover, and maintaining normal mitochondrial respiration and mitochondrial population stability

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Observational findings suggest that weight reduction achieved through GLP-1 RA therapy correlates with improved semen volume, concentration, and motility